Abstract
We investigated the consequences of colistin use in backyard chicken farms in Vietnam by examining the prevalence of mcr-1 in fecal samples from chickens and humans. Detection of mcr-1-carrying bacteria in chicken samples was associated with colistin use and detection in human samples with exposure to mcr-1-positive chickens.
Keywords:
E. coli; Vietnam; antibiotic resistance; antimicrobial resistance; backyard farm; bacteria; chicken; colistin; colistin resistance; fecal colonization; food production; poultry farms; small-scale farm; transmission; zoonoses.
MeSH terms
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Aging
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Animals
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Chickens
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Colistin / pharmacology*
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Drug Resistance, Bacterial / genetics*
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Escherichia coli / drug effects*
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Escherichia coli / genetics*
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Escherichia coli Infections / epidemiology
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Escherichia coli Infections / microbiology
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Escherichia coli Infections / veterinary
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Escherichia coli Proteins*
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Feces / microbiology
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Gene Expression Regulation, Bacterial
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Humans
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Microbial Sensitivity Tests
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Phylogeny
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Poultry Diseases / epidemiology
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Poultry Diseases / microbiology
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Risk Factors
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Vietnam
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Zoonoses*
Substances
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Escherichia coli Proteins
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MCR-1 protein, E coli
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Colistin