Abstract
We retrospectively investigated the co-occurrence of Crohn's disease in a cohort of 876 patients with Parkinson's disease, based on the observation that LRRK2 is a shared genetic risk factor. We identified 2 patients with Crohn's disease; this number was consistent with the number of cases expected in the general population.
Keywords:
Co-occurrence; Crohn's disease; LRRK2; Parkinson’s disease.
Copyright © 2017 Elsevier Ltd. All rights reserved.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
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Research Support, N.I.H., Extramural
MeSH terms
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Aged
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Aged, 80 and over
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Cohort Studies
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Crohn Disease / epidemiology*
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Crohn Disease / genetics
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Female
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Genetic Predisposition to Disease
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Humans
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Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / genetics
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Male
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Middle Aged
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Mutation / genetics
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Parkinson Disease / epidemiology*
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Parkinson Disease / genetics
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Retrospective Studies
Substances
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LRRK2 protein, human
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Leucine-Rich Repeat Serine-Threonine Protein Kinase-2