Waterhouse-Friderichsen syndrome due to Neisseria meningitidis infection in a young adult with thrombotic microangiopathy and eculizumab treatment: case report and review of management

Claudia Friedl; Gerald Hackl; Gernot Schilcher; Alexander R Rosenkranz; Kathrin Eller; Philipp Eller

doi:10.1007/s00277-017-2951-8

Waterhouse-Friderichsen syndrome due to Neisseria meningitidis infection in a young adult with thrombotic microangiopathy and eculizumab treatment: case report and review of management

Ann Hematol. 2017 May;96(5):879-880. doi: 10.1007/s00277-017-2951-8. Epub 2017 Feb 17.

Authors

Claudia Friedl¹, Gerald Hackl², Gernot Schilcher^{1

2}, Alexander R Rosenkranz¹, Kathrin Eller¹, Philipp Eller³

Affiliations

¹ Department of Internal Medicine, Clinical Division of Nephrology, Medical University Graz, Graz, Austria.
² Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, A-8036, Graz, Austria.
³ Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, A-8036, Graz, Austria. philipp.eller@medunigraz.at.

PMID: 28213751
DOI: 10.1007/s00277-017-2951-8

No abstract available

Publication types

Case Reports
Letter
Review

MeSH terms

Acute Kidney Injury / complications
Acute Kidney Injury / etiology
Acute Kidney Injury / immunology
Acute Kidney Injury / therapy
Adult
Anti-Bacterial Agents / therapeutic use
Antibodies, Monoclonal, Humanized / adverse effects*
Antibodies, Monoclonal, Humanized / therapeutic use
Ciprofloxacin / therapeutic use
Combined Modality Therapy
Disseminated Intravascular Coagulation / complications
Disseminated Intravascular Coagulation / etiology
Disseminated Intravascular Coagulation / therapy
Humans
Immunocompromised Host
Immunosuppressive Agents / adverse effects*
Immunosuppressive Agents / therapeutic use
Intensive Care Units
Lupus Erythematosus, Systemic / complications
Lupus Erythematosus, Systemic / drug therapy
Lupus Erythematosus, Systemic / immunology
Lupus Erythematosus, Systemic / physiopathology
Male
Meningococcal Infections / complications
Meningococcal Infections / drug therapy
Meningococcal Infections / microbiology
Meningococcal Infections / physiopathology*
Neisseria meningitidis, Serogroup W-135 / drug effects
Neisseria meningitidis, Serogroup W-135 / immunology*
Neisseria meningitidis, Serogroup W-135 / isolation & purification
Opportunistic Infections / complications
Opportunistic Infections / drug therapy
Opportunistic Infections / microbiology
Opportunistic Infections / physiopathology*
Severe Acute Respiratory Syndrome / complications
Severe Acute Respiratory Syndrome / etiology
Severe Acute Respiratory Syndrome / immunology
Severe Acute Respiratory Syndrome / therapy
Shock, Septic / complications
Shock, Septic / etiology
Shock, Septic / immunology
Shock, Septic / therapy
Thrombotic Microangiopathies / complications*
Thrombotic Microangiopathies / etiology
Thrombotic Microangiopathies / immunology
Thrombotic Microangiopathies / prevention & control
Treatment Outcome
Waterhouse-Friderichsen Syndrome / etiology*
Waterhouse-Friderichsen Syndrome / immunology
Waterhouse-Friderichsen Syndrome / microbiology
Waterhouse-Friderichsen Syndrome / prevention & control
Young Adult

Substances

Anti-Bacterial Agents
Antibodies, Monoclonal, Humanized
Immunosuppressive Agents
Ciprofloxacin
eculizumab