Jekyll & Hyde: The Other Life of the Death Ligand TRAIL

Mol Cell. 2017 Feb 16;65(4):585-587. doi: 10.1016/j.molcel.2017.02.004.

Authors

Najoua Lalaoui¹, John Silke²

Affiliations

¹ The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3050, Australia.
² The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3050, Australia. Electronic address: j.silke@latrobe.edu.au.

PMID: 28212746
DOI: 10.1016/j.molcel.2017.02.004

Abstract

Henry and Martin (2017) and Hartwig et al. (2017) provide more insights into the non-apoptotic function of the FADD/caspase-8 duo in TRAIL signaling.

Copyright © 2017 Elsevier Inc. All rights reserved.

MeSH terms

Apoptosis
Apoptosis Regulatory Proteins
Caspase 8
Caspases
Fas-Associated Death Domain Protein
Humans
Membrane Glycoproteins
Receptors, TNF-Related Apoptosis-Inducing Ligand*
Signal Transduction
TNF-Related Apoptosis-Inducing Ligand*
Tumor Necrosis Factor-alpha

Substances

Apoptosis Regulatory Proteins
Fas-Associated Death Domain Protein
Membrane Glycoproteins
Receptors, TNF-Related Apoptosis-Inducing Ligand
TNF-Related Apoptosis-Inducing Ligand
Tumor Necrosis Factor-alpha
Caspase 8
Caspases