1 Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy, monaco.fabrizio@hsr.it Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy, Department of Cardiothoracic and Vascular Anesthesia, Vita-Salute San Raffaele University, Milan, Italy Department of Anesthesia and Intensive Care, Academician EN Meshalkin Novosibirsk State Budget Research Institute of Circulation Pathology, Novosibirsk, Russia.