Winter is coming: Tumor cells go into hibernation

Sci Transl Med. 2017 Feb 15;9(377):eaam6063. doi: 10.1126/scitranslmed.aam6063.

Abstract

In response to hypoxia in the primary tumor microenvironment, tumor cells induce a state of dormancy enabling their persistence at metastatic sites and resistance to therapy.

Publication types

  • Comment

MeSH terms

  • Hibernation*
  • Humans
  • Hypoxia
  • Neoplasms*
  • Seasons
  • Tumor Microenvironment