PMAnalyzer: a new web interface for bacterial growth curve analysis

Bioinformatics. 2017 Jun 15;33(12):1905-1906. doi: 10.1093/bioinformatics/btx084.

Abstract

Summary: Bacterial growth curves are essential representations for characterizing bacteria metabolism within a variety of media compositions. Using high-throughput, spectrophotometers capable of processing tens of 96-well plates, quantitative phenotypic information can be easily integrated into the current data structures that describe a bacterial organism. The PMAnalyzer pipeline performs a growth curve analysis to parameterize the unique features occurring within microtiter wells containing specific growth media sources. We have expanded the pipeline capabilities and provide a user-friendly, online implementation of this automated pipeline. PMAnalyzer version 2.0 provides fast automatic growth curve parameter analysis, growth identification and high resolution figures of sample-replicate growth curves and several statistical analyses.

Availability and implementation: PMAnalyzer v2.0 can be found at https://edwards.sdsu.edu/pmanalyzer/ . Source code for the pipeline can be found on GitHub at https://github.com/dacuevas/PMAnalyzer . Source code for the online implementation can be found on GitHub at https://github.com/dacuevas/PMAnalyzerWeb .

Contact: dcuevas08@gmail.com.

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Bacteria / growth & development
  • Bacteria / metabolism*
  • Computational Biology / methods*
  • Microbiological Techniques / methods
  • Software*