The Laboratory Diagnosis of the Antiphospholipid Syndrome

Indian J Hematol Blood Transfus. 2017 Mar;33(1):8-14. doi: 10.1007/s12288-016-0739-y. Epub 2016 Oct 22.

Abstract

The Antiphospholipid Syndrome (APS) is classified based on the presence of both clinical and laboratory criteria. Both sets of criteria are subject to much review and intense research as it is becoming increasingly clear that no single test is specific for defining this autoimmune disorder. A number of leading international bodies have released guidelines in an attempt to improve the laboratory testing and reporting. The current review is an appraisal of some of the literature pertaining to the laboratory testing.

Keywords: Anti beta 2 Glycoprotein 1 antibodies; Anticardiolipin antibodies; Antiphospholipid syndrome; Laboratory tests; Lupus anticoagulant.

Publication types

  • Review