Endoscopic Management of Middle Ear Paragangliomas: A Case Series

Otol Neurotol. 2017 Mar;38(3):408-415. doi: 10.1097/MAO.0000000000001320.

Abstract

Objective: To investigate the efficacy and safety of endoscopic middle ear paraganglioma (glomus tympanicum) resection.

Study design: Case series with chart review.

Setting: Multi-institutional tertiary university medical centers.

Patients: Adult patients with middle ear paragangliomas treated via a transcanal endoscopic approach from 1/2012 to 11/2015.

Intervention: All tumors were initially approached via a transcanal endoscopic technique. An operating microscope was used only if the tumor could not be adequately visualized or resected with endoscopic techniques alone.

Main outcome measures: The main outcome was completeness of tumor resection via the endoscopic technique. Secondary measures were resolution of pulsatile tinnitus, audiometric outcomes, surgical duration, and surgical complications.

Results: Endoscopic resection was attempted on 14 middle ear paragangliomas. Thirteen patients (93%) were women with a mean age of 61.6 years. The mean tumor size was 6.2 mm (SD, 3.3). Eleven cases (79%) had complete resection via an exclusive endoscopic approach. The mean surgical duration was 108.1 minutes (SD, 55.6). One case required use of an operating microscope via a transcanal route and two cases required postauricular incisions with mastoidectomy. There were no significant postoperative complications. Two patients (14%) had tympanic membrane perforations repaired intraoperatively without residual perforation on follow-up. All patients had normal postoperative facial nerve function. Pulsatile tinnitus resolved after surgery in all 13 patients who presented with this symptom preoperatively. The mean pure-tone average improved by 5.9 dB (SD, 4.6) after surgery.

Conclusions: Endoscopic management of middle ear paraganglioma is safe, feasible, and effective.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Audiometry
  • Ear Neoplasms / pathology
  • Ear Neoplasms / surgery*
  • Ear, Middle / surgery
  • Female
  • Glomus Tympanicum Tumor / surgery*
  • Humans
  • Male
  • Middle Aged
  • Natural Orifice Endoscopic Surgery / methods*
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult