Top-down proteomics: Where we are, where we are going?

J Proteomics. 2018 Mar 20:175:3-4. doi: 10.1016/j.jprot.2017.02.002. Epub 2017 Feb 7.

Authors

Luca Fornelli¹, Timothy K Toby¹, Luis F Schachner¹, Peter F Doubleday¹, Kristina Srzentić¹, Caroline J DeHart¹, Neil L Kelleher²

Affiliations

¹ Departments of Chemistry and Molecular Biosciences, Northwestern University, 2170 Campus Drive, Evanston, IL 60208, United States.
² Departments of Chemistry and Molecular Biosciences, Northwestern University, 2170 Campus Drive, Evanston, IL 60208, United States. Electronic address: n-kelleher@northwestern.edu.

No abstract available

Keywords: Intact protein; Proteoform; Top-down proteomics.

Publication types

Editorial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Mass Spectrometry / methods
Protein Processing, Post-Translational
Proteomics / methods
Proteomics / trends*

Grants and funding