Management and Outcomes of Fetal Hydrops in a Tertiary Care Centre in Singapore

Ann Acad Med Singap. 2017 Jan;46(1):4-10.

Abstract

Introduction: Fetal hydrops is a serious condition which can be caused by immune and non-immune aetiologies. We aimed to review the management of fetal hydrops at our hospital. Materials and Methods: A retrospective review of all cases of fetal hydrops diagnosed in our institution from 2006 to 2013 was carried out. Results: Out of the 30 cases of fetal hydrops diagnosed antenatally, 17 were cases of Bart's hydrops which were all terminated in-utero. Of the remaining 13 cases, 11 cases consisted of non-immune causes of hydrops. Planned antenatal interventions including in-utero blood transfusions (n = 4) and thoracentesis (n = 5) as well as planned caesarean deliveries (n = 11) were performed in the majority of cases. Postnatal neonatal intensive care with interventions including chest drainage and transfusions were also performed. A majority, 92%, of the cases survived the perinatal period following a variable length of hospital stay ranging from a week to 3 months. Conclusion: Management of fetal hydrops is complex. Close coordination between the obstetric and neonatal teams was the key to good short-term survival of neonates with antenatally diagnosed hydrops, as it allows timely antenatal intervention and anticipation of potential perinatal complications.

MeSH terms

  • Abortion, Induced
  • Blood Transfusion*
  • Cesarean Section*
  • Disease Management
  • Drainage
  • Female
  • Fetal Therapies*
  • Hemoglobins, Abnormal
  • Humans
  • Hydrops Fetalis / blood
  • Hydrops Fetalis / etiology
  • Hydrops Fetalis / therapy*
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Pregnancy
  • Prenatal Diagnosis
  • Retrospective Studies
  • Singapore
  • Survival Rate
  • Tertiary Care Centers
  • Thoracentesis*
  • alpha-Thalassemia / blood
  • alpha-Thalassemia / complications

Substances

  • Hemoglobins, Abnormal
  • hemoglobin Bart's