Seventeen cases of histoid leprosy were found in skin out patients department of Institute of Medical Sciences in one year out of a total of 1394 cases of leprosy registered. The histoid leprosy rate is thus 1.2 %. The total lepromitous leprosy cases were 194 with which lepromatous index works out to be 13.9% About half of the histoid leprosy cases had no antileprosy treatment. Bacteriological index was high (4 to 6 + ) and morphological index renged from 20 to 70%. In this study there does not appear to be any correlation between histoid leprosy and DDS resistant strains of mycobacterium leprae.