303 randomly selected skin out-door patients were assessed with P.G.I.Health questionnaire N-2 and an open-ended life event schedule. Functional group of skin patients were found to be remarkably different from organic group with regard to the consistency in the neuroticism score within diagnostic categories of each group, effect of duration and site of lesion, and emlotlo-disturbing situations on neuroticism score. In the organic group, these variables seem to effect the N-score as a reaction to illness, whereas functional group remains unaffected. stance of pre-disposed persona pattern in functional group of skin patients could explain these findings.