Incidence and risk factors of postoperative sore throat after endotracheal intubation in Korean patients

J Int Med Res. 2017 Apr;45(2):744-752. doi: 10.1177/0300060516687227. Epub 2017 Feb 7.

Abstract

Objective To investigate the incidence of postoperative sore throat (POST) in Korean patients undergoing general anaesthesia with endotracheal intubation and to assess potential risk factors. Methods This prospective study enrolled patients who underwent all types of elective surgical procedures with endotracheal intubation and general anaesthesia. The patients were categorized into group S (those with a POST) or group N (those without a POST). The demographic, clinical and anaesthetic characteristics of each group were compared. Results This study enrolled 207 patients and the overall incidence of POST was 57.5% ( n = 119). Univariate analysis revealed that significantly more patients in group S had a cough at emergence and hoarseness in the postanaesthetic care unit compared with group N. Receiver operating characteristic curve analysis showed that an intracuff pressure ≥17 cmH2O was associated with POST. Multivariate analysis identified an intracuff pressure ≥17 cmH2O and cough at emergence as risk factors for POST. At emergence, as the intracuff pressure over ≥17 cmH2O increased, the incidence of hoarseness increased. Conclusions An intracuff pressure ≥17 cmH2O and a cough at emergence were risk factors for POST in Korean patients. Intracuff monitoring during anaesthesia and a smooth emergence are needed to prevent POST.

Keywords: Cough; intracuff pressure; intubation; sore throat.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cough / diagnosis*
  • Cough / etiology
  • Cough / physiopathology
  • Elective Surgical Procedures
  • Female
  • Hoarseness / diagnosis*
  • Hoarseness / etiology
  • Hoarseness / physiopathology
  • Humans
  • Intubation, Intratracheal / adverse effects*
  • Male
  • Middle Aged
  • Pharyngitis / diagnosis*
  • Pharyngitis / etiology
  • Pharyngitis / physiopathology
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / physiopathology
  • Postoperative Period
  • Pressure
  • Prospective Studies
  • ROC Curve
  • Risk Factors
  • Trachea / physiopathology*