Metal-organic framework mixed-matrix disks: Versatile supports for automated solid-phase extraction prior to chromatographic separation

Milad Ghani; Maria Francesca Font Picó; Shima Salehinia; Carlos Palomino Cabello; Fernando Maya; Gloria Berlier; Mohammad Saraji; Víctor Cerdà; Gemma Turnes Palomino

doi:10.1016/j.chroma.2017.01.069

Metal-organic framework mixed-matrix disks: Versatile supports for automated solid-phase extraction prior to chromatographic separation

J Chromatogr A. 2017 Mar 10:1488:1-9. doi: 10.1016/j.chroma.2017.01.069. Epub 2017 Jan 29.

Authors

Milad Ghani¹, Maria Francesca Font Picó², Shima Salehinia³, Carlos Palomino Cabello², Fernando Maya⁴, Gloria Berlier⁵, Mohammad Saraji⁶, Víctor Cerdà², Gemma Turnes Palomino⁷

Affiliations

¹ Department of Chemistry, University of the Balearic Islands, Palma de Mallorca, E-07122, Spain; Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran.
² Department of Chemistry, University of the Balearic Islands, Palma de Mallorca, E-07122, Spain.
³ Department of Chemistry, University of the Balearic Islands, Palma de Mallorca, E-07122, Spain; Department of Analytical Chemistry, Faculty of Chemistry, Kashan University, 87317-51167, Kashan, Iran.
⁴ Department of Chemistry, University of the Balearic Islands, Palma de Mallorca, E-07122, Spain. Electronic address: fernando.maya@uib.es.
⁵ University of Torino, Department of Chemistry and NIS Centre, Via P. Giuria 7, 10125 Torino, Italy.
⁶ Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran.
⁷ Department of Chemistry, University of the Balearic Islands, Palma de Mallorca, E-07122, Spain. Electronic address: g.turnes@uib.es.

PMID: 28168978
DOI: 10.1016/j.chroma.2017.01.069

Abstract

We present for the first time the application of metal-organic framework (MOF) mixed-matrix disks (MMD) for the automated flow-through solid-phase extraction (SPE) of environmental pollutants. Zirconium terephthalate UiO-66 and UiO-66-NH₂ MOFs with different size (90, 200 and 300nm) have been incorporated into mechanically stable polyvinylidene difluoride (PVDF) disks. The performance of the MOF-MMDs for automated SPE of seven substituted phenols prior to HPLC analysis has been evaluated using the sequential injection analysis technique. MOF-MMDs enabled the simultaneous extraction of phenols with the concomitant size exclusion of molecules of larger size. The best extraction performance was obtained using a MOF-MMD containing 90nm UiO-66-NH₂ crystals. Using the selected MOF-MMD, detection limits ranging from 0.1 to 0.2μgL^-1 were obtained. Relative standard deviations ranged from 3.9 to 5.3% intra-day, and 4.7-5.7% inter-day. Membrane batch-to-batch reproducibility was from 5.2 to 6.4%. Three different groundwater samples were analyzed with the proposed method using MOF-MMDs, obtaining recoveries ranging from 90 to 98% for all tested analytes.

Keywords: High performance liquid chromatography; Metal-organic frameworks; Mixed-matrix disks; Phenols; Sequential injection analysis; Solid-phase extraction.

MeSH terms

Automation
Chromatography, High Pressure Liquid / methods*
Groundwater / chemistry
Limit of Detection
Metals / chemistry*
Microscopy, Electron, Scanning
Phenols / isolation & purification
Polyvinyls / chemistry
Reference Standards
Reproducibility of Results
Rhodamines / isolation & purification
Solid Phase Extraction / methods*
Solvents
X-Ray Diffraction

Substances

Metals
Phenols
Polyvinyls
Rhodamines
Solvents
polyvinylidene fluoride
rhodamine B