Identification of a novel HLA-B*13 allele, HLA-B*13:99, by sequence-based typing in German bone marrow donor

HLA. 2017 Mar;89(3):158-159. doi: 10.1111/tan.12974. Epub 2017 Feb 5.

Abstract

Amino acid substitution Glu277Lys of the HLA-B*13:02:09 results in a novel allele, HLA-B*13:99.

Keywords: HLA-B gene; human leukocyte antigen; novel allele; sequence-based typing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Substitution
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • Gene Expression
  • Genotype
  • Germany
  • HLA-B13 Antigen / genetics*
  • HLA-B13 Antigen / immunology
  • Hematopoietic Stem Cell Transplantation
  • Histocompatibility Testing
  • Humans
  • Lithuania
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Unrelated Donors*

Substances

  • Codon
  • HLA-B13 Antigen