Surgery for rheumatic mitral valve disease in sub-saharan African countries: why valve repair is still the best surgical option

Pan Afr Med J. 2016 Aug 11:24:307. doi: 10.11604/pamj.2016.24.307.7504. eCollection 2016.

Abstract

Rheumatic valve disease, a consequence of acute rheumatic fever, remains endemic in developing countries in the sub-Saharan region where it is the leading cause of heart failure and cardiovascular death, involving predominantly a young population. The involvement of the mitral valve is pathognomonic and mitral surgery has become the lone therapeutic option for the majority of these patients. However, controversies exist on the choice between valve repair or prosthetic valve replacement. Although the advantages of mitral valve repair over prosthetic valve replacement in degenerative mitral disease are well established, this has not been the case for rheumatic lesions, where the use of prosthetic valves, specifically mechanical devices, even in poorly compliant populations remains very common. These patients deserve more accurate evaluation in the choice of the surgical strategy which strongly impacts the post-operative outcomes. This report discusses the factors supporting mitral repair surgery in rheumatic disease, according to the patients' characteristics and the effectiveness of the current repair techniques compared to prosthetic valve replacement in developing countries.

Keywords: Rheumatic heart disease; mitral valve repair; valve replacement.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Africa South of the Sahara
  • Heart Valve Diseases / etiology
  • Heart Valve Diseases / pathology
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation / methods
  • Humans
  • Mitral Valve / pathology
  • Mitral Valve / surgery*
  • Rheumatic Heart Disease / pathology
  • Rheumatic Heart Disease / surgery*