Randomized Double-Blind Controlled Trial of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Am J Respir Crit Care Med. 2017 Sep 1;196(5):656-659. doi: 10.1164/rccm.201612-2518LE.
No abstract available

Publication types

  • Clinical Trial, Phase II
  • Letter
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aminopyridines / therapeutic use*
  • Benzamides / therapeutic use*
  • Cyclopropanes / therapeutic use
  • Disease Progression
  • Double-Blind Method
  • Female
  • Forced Expiratory Volume
  • Humans
  • Leukocyte Count
  • London
  • Male
  • Middle Aged
  • Neutrophils / cytology
  • Neutrophils / immunology
  • Phosphodiesterase 4 Inhibitors / therapeutic use*
  • Pulmonary Disease, Chronic Obstructive / drug therapy*
  • Pulmonary Disease, Chronic Obstructive / immunology
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Sputum / cytology
  • Treatment Outcome

Substances

  • Aminopyridines
  • Benzamides
  • Cyclopropanes
  • Phosphodiesterase 4 Inhibitors
  • Roflumilast

Associated data

  • ClinicalTrials.gov/NCT01473758