We demonstrate all-fiber far-detuned and widely tunable mid-infrared wavelength conversion using As2Se3 microwires. In a first experiment, an idler is generated and tuned from 2.351 to >2.500 μm from four-wave mixing in a 0.5 cm long microwire. In a second experiment, tunable parametric sidebands are generated via modulation instability in a 10 cm long microwire. The resulting parametric frequency conversion reaches up to 49.3 THz, the largest ever reported in soft glass materials.