Dineolignans of 3-O-4' diphenyl ether-type from fruits of Magnolia obovata

Phytochemistry. 2017 Apr:136:133-140. doi: 10.1016/j.phytochem.2017.01.003. Epub 2017 Jan 28.

Abstract

Seven dineolignans of the 3-O-4' diphenyl ether-type (obovatalignans C-I, respectively), were isolated from fruits of Magnolia obovata through repeated silica gel (SiO2), octadecyl SiO2, and Sep-Pak chromatographies. Their chemical structures were determined based on various spectroscopic methods including NMR, HR-MS, IR, specific rotation, and CD spectrometry. Especially, compounds 1-5 include the relatively rare 1,4-benzodioxane ring moiety in the molecular structure.

Keywords: 1,4-benzodioxane type neolignan; 3-O-4′ diphenyl ether-type neolignans; Dineolignan; Magnolia obovate; Magnoliaceae; Obovatalignan.

MeSH terms

  • Fruit / chemistry*
  • Lignans / chemistry
  • Lignans / isolation & purification*
  • Magnolia / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenyl Ethers / chemistry
  • Phenyl Ethers / isolation & purification*
  • Republic of Korea
  • Silicon Dioxide / chemistry

Substances

  • Lignans
  • Phenyl Ethers
  • Silicon Dioxide