Case report of male child with elevated lipoprotein (a) leading to acute ischemic stroke

J Clin Apher. 2017 Dec;32(6):574-578. doi: 10.1002/jca.21525. Epub 2017 Jan 31.

Abstract

Acute ischemic stroke (AIS) in children is rare with almost 40% diagnosed as cryptogenic. One possible mechanism associated with AIS is an elevated Lipoprotein (a) [Lp(a)] level. Here, we discuss the case of an 11-year old boy who presented with multiple thrombotic strokes secondary to elevated Lp(a), which was identified as the only risk factor and immediately treated with lipoprotein apheresis (LA). Eighteen months post-AIS, he is still receiving LA treatments and has made remarkable progress in his recovery without another cerebrovascular event.

Keywords: acute ischemic stroke; lipoprotein (a); lipoprotein apheresis; multiple thrombotic strokes; pediatric stroke.

Publication types

  • Case Reports

MeSH terms

  • Blood Component Removal / methods
  • Child
  • Humans
  • Lipoprotein(a) / blood*
  • Lipoprotein(a) / isolation & purification
  • Male
  • Stroke / blood
  • Stroke / etiology*
  • Stroke / prevention & control
  • Thrombosis / blood

Substances

  • Lipoprotein(a)