Abstract
The challenge in achieving precision medicine relies on how to advance and/or enhance new as well as old therapeutic strategies. Here, we highlight the significant role hydrophilicity of biotinylated fluorescent probe's plays on their cellular uptake behaviour.
MeSH terms
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1-Naphthylamine / analogs & derivatives
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1-Naphthylamine / chemistry
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1-Naphthylamine / pharmacokinetics
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Biotin / analogs & derivatives*
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Biotin / pharmacokinetics
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Biotinylation
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Fluorescent Dyes / chemistry*
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Fluorescent Dyes / pharmacokinetics
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HeLa Cells
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Humans
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Hydrophobic and Hydrophilic Interactions
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Microscopy, Confocal / methods
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Microscopy, Fluorescence / methods
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Naphthalimides / chemistry
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Naphthalimides / pharmacokinetics
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Neoplasms / diagnostic imaging*
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Optical Imaging / methods*
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Quinolones / chemistry
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Quinolones / pharmacokinetics
Substances
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Fluorescent Dyes
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Naphthalimides
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Quinolones
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4-amino-1,8-naphthalimide
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Biotin
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1-Naphthylamine