Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis

Alexander V Tyakht; Veronika B Dubinkina; Vera Y Odintsova; Konstantin S Yarygin; Boris A Kovarsky; Alexander V Pavlenko; Dmitry S Ischenko; Anna S Popenko; Dmitry G Alexeev; Anastasiya Y Taraskina; Regina F Nasyrova; Evgeny M Krupitski; Nino V Shalikiani; Igor G Bakulin; Petr L Shcherbakov; Lyubov O Skorodumova; Andrei K Larin; Elena S Kostryukova; Rustam A Abdulkhakov; Sayar R Abdulkhakov; Sergey Y Malanin; Ruzilya K Ismagilova; Tatiana V Grigoryeva; Elena N Ilina; Vadim M Govorun

doi:10.1016/j.dib.2017.01.008

Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis

Data Brief. 2017 Jan 17:11:98-102. doi: 10.1016/j.dib.2017.01.008. eCollection 2017 Apr.

Authors

Alexander V Tyakht¹, Veronika B Dubinkina¹, Vera Y Odintsova², Konstantin S Yarygin³, Boris A Kovarsky², Alexander V Pavlenko³, Dmitry S Ischenko³, Anna S Popenko², Dmitry G Alexeev³, Anastasiya Y Taraskina⁴, Regina F Nasyrova⁴, Evgeny M Krupitski⁴, Nino V Shalikiani⁵, Igor G Bakulin⁵, Petr L Shcherbakov⁵, Lyubov O Skorodumova², Andrei K Larin², Elena S Kostryukova³, Rustam A Abdulkhakov⁶, Sayar R Abdulkhakov⁷, Sergey Y Malanin⁸, Ruzilya K Ismagilova⁸, Tatiana V Grigoryeva⁸, Elena N Ilina², Vadim M Govorun¹

Affiliations

¹ Moscow Institute of Physics and Technology, Institutskiy per. 9, Dolgoprudny, Moscow Region 141700, Russia.
² Federal Research and Clinical Centre of Physical-Chemical Medicine, Malaya Pirogovskaya 1a, Moscow 119435, Russia.
³ Moscow Institute of Physics and Technology, Institutskiy per. 9, Dolgoprudny, Moscow Region 141700, Russia; Federal Research and Clinical Centre of Physical-Chemical Medicine, Malaya Pirogovskaya 1a, Moscow 119435, Russia.
⁴ Saint-Petersburg Bekhterev Psychoneurological Research Institute, Bekhtereva 3, Saint-Petersburg 192019, Russia.
⁵ Moscow Clinical Scientific Center, Shosse Entuziastov 86, Moscow 111123, Russia.
⁶ Kazan State Medical University, Butlerova 49, Kazan 420012, Russia.
⁷ Kazan State Medical University, Butlerova 49, Kazan 420012, Russia; Kazan Federal University, Kremlyovskaya 18, Kazan 420008, Russia.
⁸ Kazan Federal University, Kremlyovskaya 18, Kazan 420008, Russia.

Abstract

Alcoholism is associated with significant changes in gut microbiota composition. Metagenomic sequencing allows to assess the altered abundance levels of bacterial taxa and genes in a culture-independent way. We collected 99 stool samples from the patients with alcoholic dependence syndrome (n=72) and alcoholic liver cirrhosis (n=27). Each of the samples was surveyed using "shotgun" (whole-genome) sequencing on SOLiD platform. The reads are deposited in the ENA (project ID: PRJEB18041).

Keywords: Alcohol dependence syndrome; Alcoholic liver cirrhosis; Alcoholism; Dysbiosis; Gut microbiota; Metagenome; “Shotgun” metagenomics.