Use of Phototherapy in Children

Pediatr Dermatol. 2017 Mar;34(2):150-155. doi: 10.1111/pde.13072. Epub 2017 Jan 30.

Abstract

Background: Phototherapy is a well-recognized treatment in adults and children. Previous articles have reported success in treating recalcitrant skin disorders such as atopic dermatitis (AD), psoriasis, pityriasis lichenoides chronica, and vitiligo in children.

Methods: This was a retrospective review over an 18-month period from June 2012 to December 2013 of all children receiving phototherapy in a tertiary pediatric dermatology center.

Results: Seventy-five patients 3 to 17 years of age (mean 10.6 years; 35 male, 40 female) were included. Forty-eight (64%) patients had AD and 21 (28%) had psoriasis. Seventy received narrowband ultraviolet B (NBUVB) treatment and five received hand and foot psoralen and ultraviolet A (PUVA) treatment. All patients with AD were treated with NBUVB and four (8.3%) were also treated with hand PUVA. After phototherapy, 76% had documented clear to almost clear skin. At the 12-month follow-up, 52% of the patients with AD remained clear. All 21 patients with psoriasis underwent NBUVB phototherapy. The clearance rate after phototherapy was 86%. At the 12-month follow-up, 43% of the patients with psoriasis remained clear.

Conclusion: Phototherapy can reduce disease burden in individuals with severe AD and psoriasis and should be considered as a second-line therapy if standard topical regimens are unsuccessful.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Dermatitis, Atopic / therapy*
  • Female
  • Humans
  • Male
  • Phototherapy*
  • Pityriasis Lichenoides / therapy*
  • Psoriasis / therapy*
  • Retrospective Studies
  • Treatment Outcome
  • Vitiligo / therapy*