Acute liver failure: An up-to-date approach

Filipe S Cardoso; Paulo Marcelino; Luís Bagulho; Constantine J Karvellas

doi:10.1016/j.jcrc.2017.01.003

Acute liver failure: An up-to-date approach

J Crit Care. 2017 Jun:39:25-30. doi: 10.1016/j.jcrc.2017.01.003. Epub 2017 Jan 19.

Authors

Filipe S Cardoso¹, Paulo Marcelino², Luís Bagulho², Constantine J Karvellas³

Affiliations

¹ Intensive Care Unit, Curry Cabral Hospital, Central Lisbon Hospital Center, Lisbon, Portugal. Electronic address: filipe_sousacardoso@hotmail.com.
² Intensive Care Unit, Curry Cabral Hospital, Central Lisbon Hospital Center, Lisbon, Portugal.
³ Divisions of Gastroenterology (Liver Unit) and Critical Care, University of Alberta Hospital, Edmonton, Canada.

PMID: 28131021
DOI: 10.1016/j.jcrc.2017.01.003

Abstract

Acute liver failure is a rare but potentially devastating disease. Throughout the last few decades, acute liver failure outcomes have been improving in the context of the optimized overall management. This positive trend has been associated with the earlier recognition of this condition, the improvement of the intensive care unit management, and the developments in emergent liver transplantation. Accordingly, we aimed to review the current diagnostic and therapeutic approach to this syndrome, especially in the intensive care unit setting.

Keywords: Critical care; Hepatitis; Liver failure.

Publication types

Review

MeSH terms

Critical Care / trends*
Humans
Intensive Care Units
Liver Failure, Acute / therapy*
Liver Transplantation
Referral and Consultation*