Importance of producing economic compounds to combat cancer

Microb Biotechnol. 2017 Jul;10(4):683-684. doi: 10.1111/1751-7915.12491. Epub 2017 Jan 26.

Abstract

The manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost.

Publication types

  • Comment

MeSH terms

  • Catharanthus*
  • Humans
  • Neoplasms*
  • Vinblastine

Substances

  • Vinblastine