Growing Teratoma Syndrome

Indian J Surg Oncol. 2017 Mar;8(1):46-50. doi: 10.1007/s13193-016-0568-3. Epub 2016 Oct 27.

Abstract

Growing teratoma syndrome, a disease characterized by presence of benign metastasis increasing in size and number after chemotherapy, is infrequent occurrence. Being unfamiliar with the disease entity, many oncologists misinterpret it as disease progression. Though the exact etio-pathognesis of the disease is still unidentified, but clinical characteristics are well defined. Being a chemo and radio-resistant disease, surgery offers only cure. We present a case of ovarian immature teratoma, who after chemotherapy presented with increased tumor size. Resected specimen confirms the diagnosis of mature teratoma leading to recognition of GTS. Surgery resulted in cure.

Keywords: Benign metastasis; Chemotherapeutic retroconversion; Growing teratoma syndrome; Teratoma.

Publication types

  • Review