Seroepidemiology of hepatitis B and C virus infections among blood donors in Ethiopia

J Med Virol. 2017 Jul;89(7):1300-1303. doi: 10.1002/jmv.24770. Epub 2017 Feb 27.

Abstract

This study was conducted to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among blood donors in different regions in Ethiopia. A total of 56 885 sera were tested for HBsAg and anti-HCV antibodies. Of these, 3.9% were found HBsAg-positive, 0.52% anti-HCV-positive, and 0.054% dual positive. HBV prevalence was relatively higher in Adama (5.91%) than Gondar (4.05%), Jimma (3.87%), Addis Ababa (3.75%), and Tigray (3.7%); and in males (4.64%) than females (2.1%). Overall, HBV and HCV prevalence increased with age. In conclusion, HBV and HCV seroprevalence among blood donors in Ethiopia is intermediate and low, respectively.

Keywords: HBV; HCV; ethiopia; seroepidemiology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Donors*
  • Cross-Sectional Studies
  • Ethiopia / epidemiology
  • Female
  • Hepacivirus / immunology
  • Hepacivirus / isolation & purification
  • Hepatitis B / epidemiology*
  • Hepatitis B / immunology
  • Hepatitis B / virology
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B virus / immunology
  • Hepatitis B virus / isolation & purification
  • Hepatitis C / epidemiology*
  • Hepatitis C / immunology
  • Hepatitis C / virology
  • Hepatitis C Antibodies / blood
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Seroepidemiologic Studies
  • Sex Factors
  • Young Adult

Substances

  • Hepatitis B Surface Antigens
  • Hepatitis C Antibodies