Embryonic Trogocytosis: Neighborly Nibbling during Development

Justin S A Perry; Kodi S Ravichandran

doi:10.1016/j.cub.2016.11.043

Embryonic Trogocytosis: Neighborly Nibbling during Development

Curr Biol. 2017 Jan 23;27(2):R68-R70. doi: 10.1016/j.cub.2016.11.043.

Authors

Justin S A Perry¹, Kodi S Ravichandran²

Affiliations

¹ Department of Microbiology, Immunology, and Cancer Biology and the Center for Cell Clearance, University of Virginia, Charlottesville, VA, USA.
² Department of Microbiology, Immunology, and Cancer Biology and the Center for Cell Clearance, University of Virginia, Charlottesville, VA, USA. Electronic address: Ravi@virginia.edu.

PMID: 28118592
DOI: 10.1016/j.cub.2016.11.043

Abstract

New work in Caenorhabditis elegans shows that during embryogenesis endodermal cells interact with and regulate primordial germ cells by actively excising and digesting germ cell lobes. Endodermal cells utilize proteins linked to endocytosis to perform this unique 'cannibalistic' process.

Publication types

Comment

MeSH terms

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins*
Cytophagocytosis
Embryonic Development
Endoderm
Germ Cells

Substances

Caenorhabditis elegans Proteins