Risk Factors for Postoperative Pain Intensity in Patients Undergoing Lumbar Disc Surgery: A Systematic Review

PLoS One. 2017 Jan 20;12(1):e0170303. doi: 10.1371/journal.pone.0170303. eCollection 2017.

Abstract

Objectives: Pain relief has been shown to be the most frequently reported goal by patients undergoing lumbar disc surgery. There is a lack of systematic research investigating the course of postsurgical pain intensity and factors associated with postsurgical pain. This systematic review focuses on pain, the most prevalent symptom of a herniated disc as the primary outcome parameter. The aims of this review were (1) to examine how pain intensity changes over time in patients undergoing surgery for a lumbar herniated disc and (2) to identify socio-demographic, medical, occupational and psychological factors associated with pain intensity.

Methods: Selection criteria were developed and search terms defined. The initial literature search was conducted in April 2015 and involved the following databases: Web of Science, Pubmed, PsycInfo and Pubpsych. The course of pain intensity and associated factors were analysed over the short-term (≤ 3 months after surgery), medium-term (> 3 months and < 12 months after surgery) and long-term (≥ 12 months after surgery).

Results: From 371 abstracts, 85 full-text articles were reviewed, of which 21 studies were included. Visual analogue scales indicated that surgery helped the majority of patients experience significantly less pain. Recovery from disc surgery mainly occurred within the short-term period and later changes of pain intensity were minor. Postsurgical back and leg pain was predominantly associated with depression and disability. Preliminary positive evidence was found for somatization and mental well-being.

Conclusions: Patients scheduled for lumbar disc surgery should be selected carefully and need to be treated in a multimodal setting including psychological support.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Humans
  • Lumbar Vertebrae / surgery*
  • Orthopedic Procedures / adverse effects*
  • Pain Measurement*
  • Pain, Postoperative / diagnosis*
  • Pain, Postoperative / physiopathology
  • Pain, Postoperative / therapy
  • Risk Factors
  • Treatment Outcome

Grants and funding

We acknowledge support from the German Research Foundation (DFG) and Universität Leipzig within the program of Open Access Publishing.