Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring blaNDM-1

Yancheng Yao; Linda Falgenhauer; Volkhard A J Kempf; Michael Hogardt; Stephan Göttig; Can Imirzalioglu; Trinad Chakraborty

doi:10.1128/genomeA.01481-16

Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring blaNDM-1

Genome Announc. 2017 Jan 19;5(3):e01481-16. doi: 10.1128/genomeA.01481-16.

Authors

Yancheng Yao¹, Linda Falgenhauer¹, Volkhard A J Kempf², Michael Hogardt², Stephan Göttig², Can Imirzalioglu¹, Trinad Chakraborty³

Affiliations

¹ Institute of Medical Microbiology, German Center for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig University Giessen, Giessen, Germany.
² Institute for Medical Microbiology and Infection Control, University Hospital, Goethe-University, Frankfurt am Main, Germany.
³ Institute of Medical Microbiology, German Center for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig University Giessen, Giessen, Germany trinad.chakraborty@mikrobio.med.uni-giessen.de.

Abstract

The draft genome sequences of two clonal, pandrug-resistant Serratia marcescens clinical isolates were determined. The resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large IncFIB(K), IncHI2, and IncA/C2 plasmids indicating a large pool of transmissible antibiotic resistance genes.