Collapse of human scalp microbiome network in dandruff and seborrhoeic dermatitis

Abstract

We investigate the relationship between scalp microbiota and dandruff/seborrhoeic dermatitis (D/SD), an unpleasant scalp disorder common in human populations. Bacterial and fungal community analyses on scalp of 102 Korean were performed by next-generation sequencing. Overall scalp microbiome composition significantly differed between normal and disease groups, and especially co-occurrence network of dominant members was breakdown in disease groups. These findings will provide novel insights into shifts of microbial community relevant to D/SD.

Keywords: dandruff; next generation sequencing; scalp microbiome; seborrheic dermatitis.