Surface-mounted MOF templated fabrication of homochiral polymer thin film for enantioselective adsorption of drugs

Chem Commun (Camb). 2017 Jan 26;53(9):1470-1473. doi: 10.1039/c6cc08342k.

Abstract

A self-polymerized chiral monomer 3,4-dihydroxy-l-phenylalanine (l-DOPA) has been introduced into the pores of an achiral surface-mounted metal organic framework (SURMOF), and then the homochiral poly(l-DOPA) thin film has been successfully formed after UV light irradiation and etching of the SURMOF. Remarkably, such a poly(l-DOPA) thin film exhibited enantioselective adsorption of naproxen. This study opened a SURMOF-templated approach for preparing porous polymer thin films.

MeSH terms

  • Adsorption
  • Dihydroxyphenylalanine / analogs & derivatives*
  • Dihydroxyphenylalanine / chemistry
  • Metal-Organic Frameworks / chemistry*
  • Naproxen / chemistry*
  • Polymers / chemistry*
  • Porosity
  • Stereoisomerism
  • Surface Properties
  • Ultraviolet Rays

Substances

  • Metal-Organic Frameworks
  • Polymers
  • poly(3,4-dihydroxyphenylalanine)
  • Naproxen
  • Dihydroxyphenylalanine