Mechanisms on spasmolytic and anti-inflammatory effects of a herbal medicinal product consisting of myrrh, chamomile flower, and coffee charcoal

Wien Med Wochenschr. 2017 May;167(7-8):169-176. doi: 10.1007/s10354-016-0538-y. Epub 2017 Jan 13.

Abstract

Inflammatory bowel disease or irritable bowel syndrome are chronic gastrointestinal disorders which are associated with a lifelong therapeutic need. The disease results in physical, psychological, and social problems with an impact on partnership, sexuality, education, and career. Thus, the number of patients and health care professionals relying on traditional and complementary medicines and especially phytotherapy for the treatment of these chronic conditions is increasing over recent years. One traditional herbal medicinal product consisting of chamomile flower, myrrh, and coffee charcoal has been widely used in clinical practice within this indication area. Long-term experience and an increasing understanding of the pharmacological mechanisms substantiate its application and clinical effectiveness. Mainly the spasmolytic and anti-inflammatory effects provide a rationale for its therapeutic application. In addition, synergistic effects between the herbal components contribute to the overall effect of this medication.

Keywords: Chamomile flower; Coffee charcoal; Inflammatory bowel disease; Intestinal motility; Myrrh.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Chamomile*
  • Charcoal / therapeutic use*
  • Coffee
  • Commiphora*
  • Flowers*
  • Humans
  • Inflammatory Bowel Diseases / drug therapy*
  • Parasympatholytics / therapeutic use
  • Phytotherapy*
  • Plant Extracts / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Coffee
  • Parasympatholytics
  • Plant Extracts
  • Charcoal