Draft Genome Sequence of an Anicemycin Producer, Streptomyces sp. TP-A0648

Hisayuki Komaki; Akira Hosoyama; Akane Kimura; Natsuko Ichikawa; Yasuhiro Igarashi

doi:10.1128/genomeA.01468-16

Draft Genome Sequence of an Anicemycin Producer, Streptomyces sp. TP-A0648

Genome Announc. 2017 Jan 12;5(2):e01468-16. doi: 10.1128/genomeA.01468-16.

Authors

Hisayuki Komaki¹, Akira Hosoyama², Akane Kimura², Natsuko Ichikawa², Yasuhiro Igarashi³

Affiliations

¹ Biological Resource Center, National Institute of Technology and Evaluation (NBRC), Chiba, Japan komaki-hisayuki@nite.go.jp.
² NBRC, Tokyo, Japan.
³ Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, Toyama, Japan.

Abstract

We report the draft genome sequence of Streptomyces sp. TP-A0648 isolated from a leaf of Aucuba japonica This strain produces a new tumor cell growth inhibitor designated anicemycin. The genome harbors at least 12 biosynthetic gene clusters for polyketides and nonribosomal peptides, suggesting the potential to produce diverse secondary metabolites.