How Meiosis Creates the Single-Copy Genome

Mary Herbert; Attila Toth

doi:10.1016/j.devcel.2016.12.019

How Meiosis Creates the Single-Copy Genome

Dev Cell. 2017 Jan 9;40(1):3-4. doi: 10.1016/j.devcel.2016.12.019.

Authors

Mary Herbert¹, Attila Toth²

Affiliations

¹ Newcastle Fertility Centre, Institute of Genetic Medicine, Newcastle University, Centre for Life, Times Square, Newcastle upon Tyne NE1 4EP, UK. Electronic address: mary.herbert@newcastle.ac.uk.
² Institute of Physiological Chemistry, Medical Faculty of TU Dresden, Fiedlerstrasse 42, 01307 Dresden, Germany. Electronic address: attila.toth@mailbox.tu-dresden.de.

PMID: 28073009
DOI: 10.1016/j.devcel.2016.12.019

Abstract

Genome haploidization involves two meiotic divisions following a single round of DNA replication. In this issue of Developmental Cell, Argüello-Miranda et al. (2017) show that production and packaging of the single-copy genome into gametes during the second meiotic division is coordinated by a conserved casein kinase 1.

Publication types

Comment

MeSH terms

DNA Replication*
Meiosis*

Grants and funding

MR/J003603/1/MRC_/Medical Research Council/United Kingdom