Biomimetically crystallized protease resistant zinc phosphate decorated with gold atomic clusters for bioimaging

Chem Commun (Camb). 2017 Jan 19;53(7):1277-1280. doi: 10.1039/c6cc09092c.

Abstract

A luminescent probe synthesised via biomimetic crystallization of zinc phosphate in the presence of protein fragment stabilised gold (Au) nanoclusters is reported. The engineered probe - with Au nanoclusters assembled on the crystal - was protease resistant and offered efficient bioimaging and uptake studies.

MeSH terms

  • Biomimetic Materials / chemistry*
  • Crystallization
  • Gold / chemistry*
  • HeLa Cells
  • Humans
  • Luminescent Agents / analysis
  • Luminescent Agents / chemical synthesis*
  • Metal Nanoparticles / chemistry*
  • Molecular Imaging / methods
  • Optical Imaging / methods*
  • Peptide Hydrolases / metabolism*
  • Phosphates / chemistry*
  • Zinc Compounds / chemistry*

Substances

  • Luminescent Agents
  • Phosphates
  • Zinc Compounds
  • zinc phosphate
  • Gold
  • Peptide Hydrolases