[Febrile ulceronecrotic Mucha-Habermann disease]

Rev Med Chil. 2016 Sep;144(9):1214-1217. doi: 10.4067/S0034-98872016000900017.
[Article in Spanish]

Abstract

Pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic Mucha-Habermann disease (FUMHD) are considered different manifestations of the same disease. Febrile ulceronecrotic Mucha-Habermann disease is a rare, and potentially lethal illness which is characterized by fast progression of numerous papules that converge, ulcerate and form a plaque with a necrotic center, together with hemorrhagic vesicles and pustules that are associated with high fever and variable systemic symptoms. We report a 16 years old male presenting with erythematous papules with crusts and fever. The diagnosis of febrile ulceronecrotic Mucha-Habermann disease was confirmed with the pathological study of the lesions. He was successfully treated with minocycline after a failed attempt of treatment with prednisone.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Inflammatory Agents / therapeutic use*
  • Herpes Simplex / drug therapy*
  • Herpes Simplex / pathology
  • Humans
  • Male
  • Minocycline / therapeutic use*
  • Pityriasis Lichenoides / drug therapy*
  • Pityriasis Lichenoides / pathology
  • Prednisone / therapeutic use*
  • Skin Ulcer / pathology
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Minocycline
  • Prednisone

Supplementary concepts

  • Febrile Ulceronecrotic Mucha-Habermann disease