Temperature increase induced by modulated electrohyperthermia (oncothermia®) in the anesthetized pig liver

J Cancer Res Ther. 2016 Jul-Sep;12(3):1153-1159. doi: 10.4103/0973-1482.197561.

Abstract

Aim of study: Is to show the intrahepatic temperature development in anesthetized pig.

Materials and methods: Temperature development in the liver of anesthetized pig is measured to study the thermal effects of capacitive coupled energy transfer. The treatment was made by modulated electrohyperthermia (mEHT, trade name: oncothermia ®), controlled by a fluoroptical temperature sensing positioned by the ultrasound-guided process. Various fits of coupling were studied.

Results: The intrahepatic temperature at the end of the treatment ranged 40.5-44.8°C, while the skin temperature ranged 36.8-41.8°C depending on the coupling arrangement.

Conclusion: mEHT is a feasible method to deliver deep heat to the liver of an anesthetized pig.

MeSH terms

  • Anesthesia*
  • Animals
  • Electrodes
  • Hyperthermia, Induced*
  • Liver / drug effects*
  • Liver / radiation effects*
  • Models, Animal
  • Swine
  • Temperature*
  • Thermometers