Cirrhosis and liver transplantation in patients co-infected with HIV and hepatitis B or C: an observational cohort study

Infection. 2017 Apr;45(2):215-220. doi: 10.1007/s15010-016-0976-x. Epub 2017 Jan 4.

Abstract

This study assessed the likelihood of referral for liver transplantation assessment in a prospective cohort of patients co-infected with HIV and hepatitis B or C with complications of cirrhosis. There were 141 co-infected patients from 11 UK centres with at least one complication of cirrhosis recorded (either decompensation or hepatocellular carcinoma) out of 772 identified with cirrhosis and/or HCC. Only 23 of these 141 (16.3%) were referred for liver transplantation assessment, even though referral is recommended for co-infected patients after the first decompensation episode.

Keywords: Cirrhosis; Co-infection; HIV; Hepatitis B; Hepatitis C; Liver transplantation.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Adult
  • Coinfection / complications*
  • Female
  • HIV Infections / complications*
  • Hepatitis B, Chronic / complications*
  • Hepatitis C, Chronic / complications*
  • Humans
  • Liver Cirrhosis / epidemiology*
  • Liver Cirrhosis / surgery*
  • Liver Transplantation*
  • Male
  • Middle Aged
  • Prospective Studies
  • United Kingdom