Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma

Selene Baos; David Calzada; Lucía Cremades; Joaquín Sastre; Joaquín Quiralte; Fernando Florido; Carlos Lahoz; Blanca Cárdaba

doi:10.1016/j.dib.2016.12.035

Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma

Data Brief. 2016 Dec 22:10:505-510. doi: 10.1016/j.dib.2016.12.035. eCollection 2017 Feb.

Authors

Selene Baos¹, David Calzada², Lucía Cremades², Joaquín Sastre³, Joaquín Quiralte⁴, Fernando Florido⁵, Carlos Lahoz¹, Blanca Cárdaba¹

Affiliations

¹ Immunology Department, IIS- Jiménez Díaz Foundation, UAM, Madrid, Spain; CIBERES, CIBER of Respiratory Diseases, Spain.
² Immunology Department, IIS- Jiménez Díaz Foundation, UAM, Madrid, Spain.
³ CIBERES, CIBER of Respiratory Diseases, Spain; Allergy Department, Jiménez Díaz Foundation, Madrid, Spain.
⁴ Allergy Department, Vírgen del Rocío University Hospital, Seville, Spain.
⁵ Allergy Department, San Cecilio University Hospital, Granada, Spain.

Abstract

This article contains information related to the research article entitled "Biomarkers associated with disease severity in allergic and nonallergic asthma" (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population (n=104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research.

Keywords: Allergy; Asthma; Biomarkers; Gene expression; Peripheral samples.