Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women

Appl Physiol Nutr Metab. 2017 Feb;42(2):216-227. doi: 10.1139/apnm-2016-0456. Epub 2017 Jan 3.

Abstract

While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (-4.32 kg; 95% CI, -5.75, -2.88), WW (-4.31 kg; 95% CI, -5.82, -2.96), JC (-5.34 kg; 95% CI, -6.86, -3.90), NS (-5.03 kg; 95% CI, -6.49, -3.56), and control (0.16 kg, 95% CI, -1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but not WW (31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = -0.7), NS (39% vs. 50% adjres. = -1.5), or control (45% vs. 55% adjres. = -1.7). While all groups improved relative fitness (mL·kg-1·min-1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.

Keywords: diet; diète; exercice physique; exercise; metabolic syndrome; syndrome métabolique.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Body Mass Index
  • Cardiorespiratory Fitness
  • Combined Modality Therapy / economics
  • Diet, Reducing* / economics
  • Double-Blind Method
  • Energy Intake
  • Exercise*
  • Female
  • Follow-Up Studies
  • Humans
  • Insulin Resistance
  • Metabolic Syndrome / epidemiology
  • Metabolic Syndrome / etiology
  • Metabolic Syndrome / prevention & control*
  • Middle Aged
  • Obesity / diet therapy*
  • Obesity / metabolism
  • Obesity / physiopathology
  • Obesity / therapy
  • Overweight / diet therapy*
  • Overweight / metabolism
  • Overweight / physiopathology
  • Overweight / therapy
  • Patient Compliance
  • Prevalence
  • Resistance Training
  • Risk Factors
  • Sedentary Behavior
  • Texas / epidemiology
  • Weight Loss