Drug metabolism and pancreatic cancer

Ann Gastroenterol. 2017;30(1):54-61. doi: 10.20524/aog.2016.0074. Epub 2016 Jul 21.

Abstract

Pancreatic cancer remains a fatal disease in the majority of patients. The era of personalized medicine is upon us: customizing therapy according to each patient's individual cancer. Potentially, therapy can be targeted at individuals who would most likely have a favorable response, making it more efficacious and cost effective. This is particularly relevant for pancreatic cancer, which currently portends a very poor prognosis. However, there is much to be done in this field, and more studies are needed to bring this concept to reality.

Keywords: Chemotherapy; genomic profile; genomics; molecular pancreatic pathogenesis; pancreatic cancer pharmacogenomics; pancreatic exocrine cancer; targeted therapy.

Publication types

  • Review