Vitamin D: Musculoskeletal health

Rev Endocr Metab Disord. 2017 Sep;18(3):363-371. doi: 10.1007/s11154-016-9404-x.

Abstract

Perhaps the role of Vitamin D supplementation has been most exhaustively studied in calcium absorption, skeletal wellbeing, muscular potency, balance and risk of falling. Nonetheless, new data has emerged and the recent research on sarcopenia makes the topic increasingly interesting. Given the socioeconomic burden of the musculoskeletal consequences of hypovitaminosis D it is vital to keep abreast with the latest literature in the field. The recommended Vitamin D supplementation dose should suffice to increase the serum 25 hydroxyvitamin D level to 30 ng/mL (75 nmol/L) and this level should be optimally maintained with a maintenance dose, particularly for those diagnosed with osteoporosis.

Keywords: Bone; Falls; Muscle; Osteoporosis; Sarcopenia; Vitamin D.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Density / drug effects
  • Bone Density / physiology*
  • Calcium, Dietary / pharmacology
  • Dietary Supplements
  • Health
  • Humans
  • Musculoskeletal Physiological Phenomena* / drug effects
  • Osteoporosis / diet therapy
  • Osteoporosis / prevention & control
  • Vitamin D / pharmacology
  • Vitamin D / physiology*
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / complications

Substances

  • Calcium, Dietary
  • Vitamin D