Surgical treatment of salivary malignant tumors

Oral Oncol. 2017 Feb:65:102-113. doi: 10.1016/j.oraloncology.2016.12.007. Epub 2016 Dec 22.

Abstract

Salivary gland malignant tumors (SGMT) are of key interest for head and neck surgeons since surgery with adjuvant radiotherapy is considered the treatment of choice in most of the cases. Some factors, namely rarity, high histologic heterogeneity, and possible occurrence in all the head and neck subsites, contribute to make this topic very controversial; some unclear aspects pertain surgical treatment. When dealing with major salivary gland malignant tumors (MaSGMT), the most debated issues remain the extent of surgery and management of facial nerve. In minor salivary gland malignant tumors (MiSGMT), conversely, surgical planning is influenced by the specific pattern of growth of the different neoplasms as well as the site of origin of the lesion. Finally, two additional issues, the treatment of the neck (therapeutic or elective) and reconstructive strategy after ablative surgery, are of pivotal importance in management of both MaSGMT and MiSGMT. In this review, we discuss the most relevant and controversial issues concerning surgery of SGMT.

Keywords: Malignant tumor; Minor salivary gland; Neck; Parotid; Sublingual gland; Submandibular gland; Surgery.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Lymphatic Metastasis / pathology
  • Salivary Gland Neoplasms / pathology
  • Salivary Gland Neoplasms / surgery*