Oncogenic hypophosphatemic osteomalacia: From the first signal of disease to the first signal of healthy

Arthur Paredes Gatti; Luiza Tonello; João Alfredo Diedrich Neto; Uirá Fernandes Teixeira; Marcos Bertozzi Goldoni; Paulo Roberto Ott Fontes; José Artur Sampaio; Luiz Maraninchi Pereira Lima; Fábio Luiz Waechter

doi:10.1016/j.ijscr.2016.11.037

Oncogenic hypophosphatemic osteomalacia: From the first signal of disease to the first signal of healthy

Int J Surg Case Rep. 2017:30:130-133. doi: 10.1016/j.ijscr.2016.11.037. Epub 2016 Nov 27.

Authors

Arthur Paredes Gatti¹, Luiza Tonello², João Alfredo Diedrich Neto², Uirá Fernandes Teixeira², Marcos Bertozzi Goldoni², Paulo Roberto Ott Fontes², José Artur Sampaio², Luiz Maraninchi Pereira Lima², Fábio Luiz Waechter²

Affiliations

¹ General Surgery Unit, Universidade Federal De Ciências Da Saúde De Porto Alegre, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS 90050-170, Brazil. Electronic address: arthurpgatti@hotmail.com.
² General Surgery Unit, Universidade Federal De Ciências Da Saúde De Porto Alegre, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS 90050-170, Brazil.

Abstract

Introduction: The physical incapacitation of the oncogenic hypophosphatemic osteomalacia (OHO) can be catastrophic and can lead to deformities, metabolic and organic instability and death. The only positive outcome is through early diagnosis by the clinical suspicion. At this moment, medical center infrastructure is also a keypoint.

Presentation of case: This case report is about a 60-year old woman with multiple fractures, gradual loss of strength and muscle mass and limiting deformities in two years of evolution until the diagnostic.

Discussion: The lack of knowledge of this disease causes a delay in diagnosis that can bring deformities to the patient, as well as death. Is crucial that is hypothesized to carry out the necessary tests, since they are expensive and not always available.

Conclusion: This case reinforces the importance to understand the OHO and tumoral search, once this lesion is, in most cases, imperceptible to physical examination or several imaging studies.

Keywords: Cancer; Oncogenic osteomalacia; Tumor.