A Quick Reference on Chloride

Andrea A Bohn; Helio Autran de Morais

doi:10.1016/j.cvsm.2016.10.008

A Quick Reference on Chloride

Vet Clin North Am Small Anim Pract. 2017 Mar;47(2):219-222. doi: 10.1016/j.cvsm.2016.10.008. Epub 2016 Dec 20.

Authors

Andrea A Bohn¹, Helio Autran de Morais²

Affiliations

¹ Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523, USA. Electronic address: Andrea.Bohn@ColoState.EDU.
² Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, 700 Southwest 30th Street, Magruder Hall, Corvallis, OR 97331, USA.

PMID: 28007306
DOI: 10.1016/j.cvsm.2016.10.008

Abstract

Chloride is an essential element, playing important roles in digestion, muscular activity, regulation of body fluids, and acid-base balance. As the most abundant anion in extracellular fluid, chloride plays a major role in maintaining electroneutrality. Chloride is intrinsically linked to sodium in maintaining osmolality and fluid balance and has an inverse relationship with bicarbonate in maintaining acid-base balance. It is likely because of these close ties that chloride does not get the individual attention it deserves; we can use these facts to simplify and interpret changes in serum chloride concentrations.

Keywords: Analysis; Chloride; Reference; Sodium bicarbonate.

Publication types

Review

MeSH terms

Acid-Base Imbalance / diagnosis
Acid-Base Imbalance / veterinary*
Animals
Chlorides / metabolism*
Chlorides / pharmacology
Reference Values
Sodium Bicarbonate / pharmacology

Substances

Chlorides
Sodium Bicarbonate