Detection of Bovine Viral Diarrhoea Virus 2 as the Cause of Abortion Outbreaks on Commercial Sheep Flocks

Transbound Emerg Dis. 2017 Feb;64(1):19-26. doi: 10.1111/tbed.12599. Epub 2016 Dec 21.

Abstract

Outbreaks of abortions and lambs born with nervous clinical signs and/or congenital malformations affected different sheep farms in Spain. Initial diagnosis of 'border disease-like' was established, based on clinical signs, serology and/or RNA detection by a pan-pestivirus RT-PCR. However, further investigation using immunohistochemical and molecular techniques identified BVDV-2b as the aetiological agent.

Keywords: BVDV-2; abortion; antigenic typing; bovine viral diarrhoea virus; sheep.

MeSH terms

  • Abortion, Veterinary / virology*
  • Animals
  • Cattle
  • Diarrhea Virus 2, Bovine Viral / isolation & purification*
  • Disease Outbreaks / veterinary*
  • Female
  • Pestivirus Infections / epidemiology
  • Pestivirus Infections / veterinary*
  • Pregnancy
  • Sheep
  • Sheep Diseases / epidemiology
  • Sheep Diseases / virology*
  • Spain / epidemiology

Associated data

  • GENBANK/KX369602
  • GENBANK/KX369603
  • GENBANK/KX369604
  • GENBANK/KX369605
  • GENBANK/KX369606
  • GENBANK/KX369607