An examination of 2033 patients has established that the conditions for the development of pyo-septic and pulmonary complications of a severe trauma appear in the period of shock. Each kind of complications of trauma disease is associated with a certain set of risk factors. The localization, character of the injury and kind of early posttraumatic intoxication are responsible for the structure of complication. The blood loss value and volume of the infusion-transfusion therapy are considered to be the most common risk factors of the development of complications.