Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia

Steven Goossens; Pieter Van Vlierberghe

doi:10.1371/journal.pmed.1002208

Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia

PLoS Med. 2016 Dec 20;13(12):e1002208. doi: 10.1371/journal.pmed.1002208. eCollection 2016 Dec.

Authors

Steven Goossens^{1

2

3}, Pieter Van Vlierberghe^{1

3}

Affiliations

¹ Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
² Department for Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
³ Cancer Research Institute Ghent (CRIG), Ghent, Belgium.

Abstract

In a Perspective, Pieter Van Vlierberghe and Steven Goossens discuss Meijerink and colleagues' findings on steroid resistance in pediatric T cell acute lymphoblastic leukemia.

MeSH terms

Adolescent
Antineoplastic Agents / pharmacology*
Child
Child, Preschool
Drug Resistance, Neoplasm / drug effects*
Humans
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Steroids / pharmacology*

Substances

Antineoplastic Agents
Steroids

Grants and funding

The authors received no funding for this work.